Know how and applications

Particle Size Measurement with SALD Devices

Particle size measurement is an essential step in many research and development processes, spanning fields from pharmaceuticals to chemistry and materials science. With Shimadzu’s SALD (Scattering Analysis by Laser Diffraction) devices, measuring particle size becomes efficient, precise, and reliable. These devices use laser diffraction to analyze the size and distribution of particles in liquids, powders, or suspensions, providing comprehensive data crucial for quality control and product development.

How Does Particle Size Measurement with SALD Work?

Shimadzu’s SALD devices utilize the laser diffraction method. A laser beam is directed at the particle sample, and the particles scatter the light in various directions. The scattering pattern is captured and analyzed by a detector. The angles and intensities of the scattered light are directly related to the particle size:

  • Large Particles: Scatter light at smaller angles.
  • Small Particles: Scatter light at larger angles.

The device calculates the size and distribution of particles based on these scattering patterns. Thanks to highly sensitive detectors and advanced analysis algorithms, even mixtures of particles of different sizes can be measured with precision.

 

Key Features of SALD Devices:

Shimadzu’s SALD devices offer several technical advantages that make them ideal for demanding measurement tasks in both laboratory and production environments:

  • Wide Measurement Range: The devices can measure a broad spectrum of particle sizes, from nanometers to several millimeters. This makes them suitable for both fine powders and larger particle mixtures.
  • High Measurement Accuracy: With advanced laser technology and sensitive detectors, SALD devices deliver highly accurate results. This accuracy is crucial for quality control, such as in pharmaceutical products where particle size affects the effectiveness and release of active ingredients.
  • Fast Analysis: SALD devices enable real-time measurement of particle size. This is particularly useful for process monitoring in production, allowing for immediate adjustments.
  • Versatile Applications: The SALD series from Shimadzu includes models designed for both liquid and dry samples. This covers a wide range of materials and applications, from suspension analysis to powder particle examination.

 

Why is Particle Size Measurement Important?

Particle size significantly impacts the properties and behavior of materials. In pharmaceuticals, it affects drug solubility and release rates. In the chemical industry, it determines the reaction rate of substances. In materials science and the production of construction materials like cement or ceramics, particle size distribution is crucial for the mechanical properties of the final product. Precise measurement with Shimadzu’s SALD devices allows for targeted control and optimization of these properties.

 

Our Expertise with SALD Devices at Shimadzu

At Shimadzu, we use state-of-the-art SALD devices to perform particle size measurement with the highest accuracy. Our experienced experts assist you in analyzing and interpreting measurement results, ensuring you receive reliable data for quality control and product development. With particle size analysis, we work together to optimize your processes and ensure your products meet the highest quality standards.

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FAQs: About Particle Size Measurement with SALD Devices

1. What is particle size measurement?

Particle size measurement is the process of determining the size and distribution of particles within a sample. It is crucial for understanding material properties and performance in various applications, including pharmaceuticals, chemicals, and materials science.

SALD (Scattering Analysis by Laser Diffraction) devices measure particle size using laser diffraction technology. A laser beam is directed at a sample, and the scattered light is analyzed to determine the size and distribution of the particles based on the angle and intensity of the scattered light.

SALD devices can analyze a wide range of samples, including powders, liquids, and suspensions. This versatility makes them suitable for diverse applications across industries like pharmaceuticals, materials science, and environmental monitoring.

SALD devices offer a broad measurement range, typically from nanometers to several millimeters. This allows them to accurately measure both very fine powders and larger particles, making them suitable for various material types and applications.

SALD devices are known for their high accuracy and precision. They use advanced laser technology and sensitive detectors to provide detailed and reliable particle size distributions. The accuracy of the measurement depends on factors such as sample preparation and instrument calibration.

SALD devices deliver rapid results, often in just a few minutes. This fast measurement capability is particularly beneficial for real-time process monitoring and quality control in manufacturing environments.

Key benefits include:

  • High Precision: Accurate and reliable particle size distributions.
  • Wide Range: Ability to measure a broad spectrum of particle sizes.
  • Fast Analysis: Quick measurement times for efficient testing.
  • Versatility: Suitable for both dry powders and liquid samples.

Yes, many SALD devices are equipped to provide real-time measurements. This capability is useful for monitoring and controlling processes in manufacturing or other dynamic environments where particle size distribution needs to be continuously tracked.

Proper sample preparation is crucial for accurate measurements. Ensure that the sample is well-dispersed and free of agglomerates or contaminants. For powders, use appropriate dispersion methods, and for liquids, ensure the sample is well mixed.

SALD devices are widely used in various industries and research fields, including:

  • Pharmaceuticals: To analyze particle size distribution of drug formulations, affecting drug release rates and effectiveness.
  • Chemicals: For quality control of chemical powders and granular materials.
  • Materials Science: To study the size and distribution of particles in materials like ceramics, metals, and composites.
  • Environmental Monitoring: To measure particle sizes in air or water samples, important for assessing pollution levels.

Machines for Particle Size Measurement

Knowledge in materials testing

Material testing is crucial for material quality and safety. Various technologies such as non-destructive testing, tensile testing and bending testing are used. Standards and regular calibration of testing machines are essential to ensure accurate results. Frequently asked questions (FAQs) provide additional information.

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